← All Services

Lead Design

Lead Design & Optimization

Turn your hit series into a clear synthesis roadmap. We identify SAR trends, design analogs, and flag ADMET liabilities — so your next round is built on evidence.

Who It's For

You have confirmed hits and need a clear next-round synthesis strategy

You want to understand which parts of your compound drive activity

Your compounds have ADMET liabilities you need to resolve

You need analog proposals to guide your medicinal chemistry team

Key Deliverables

SAR reportBinding mode analysisAnalog proposalADMET liability reportProperty optimization strategyNext synthesis priority listMedicinal chemistry strategy memo

Packages

01

SAR Modeling

Binding mode analysis and SAR interpretation for your existing hit series.

02

Analog Design Sprint

SAR-based analog proposals with ADMET and property profiling for next-round synthesis.

03

ADMET Liability Analysis

Identify and address ADMET liabilities through physicochemical property optimization.

04

Monthly Lead Design Cycle

Ongoing monthly support — design cycles, decision memos, and candidate reviews.

Exact scope and pricing provided after a brief consultation.

Ready to optimize your leads?

Share your hit series and we will propose the right design and optimization strategy.

Contact Us →